Gan Mai Da Zao Tang was first in Jin Gui Yao Lue (a classic medical book was written by Zhang Zhong Jing for treating Zang Zao, in which female patients feel sadness, tend to cry, lose interest and focus, yawn frequently. There are only 3 types of herbs in this formula: Glycyrrhiza uralensis Fisch. (licorice), Triticum aestivum L. (wheat) and Zizphus jujuba Mill. (jujube). This formula is commonly used to treat anxiety, depression, stress, insomnia, menopause syndrome etc. In